Another person who does not have children said that it would have been a deal breaker for them as well.
Some people backed the OP’s wife, saying she knew her limits and couldn’t handle caring for a child going through such extreme trauma.
Someone else chimed in and said that the OP’s wife would be forced into the position of mother if she helped raise his sister even if she didn’t want to.
Another poster said that they would normally side with the wife, but in this case they couldn’t since they felt the wife had been unfair to the OP and his sister by making the accusation that he preferred her to her.