In some cases, the cancer itself or surrounding inflammation can partially block the passage of food from the stomach into the small intestine, leading to feelings of sickness. As a result, you may lose your appetite, which can contribute to unintentional weight loss.
Weight loss
Unexplained weight loss can be a sign of pancreatic cancer.
Since the pancreas helps with digestion and regulates blood sugar, …can interfere with these functions, leading to difficulty absorbing nutrients and resulting in weight loss—even if you’re eating normally.
Source: Brightside